Endocrine Abstracts

Spexin is a novel peptide which has a potential role as a biomarker of insulin resistance, diabetes and obesity. We aimed to investigate spexin levels in lean type 1 diabetes patients and spexin’s role on glycemic parameters without the presence of obesity or insulin resistance.Patients and methods: This cross-sectional study included 29 type 1 diabetic patients and a control group of 23 healthy subjects adjusted for age, sex and body mass index (BM...

Background: Enviromental factors such as life style changes and dieatary factors become more important on the background of coronary artery disease (CAD). The thiols were the main part of the non-enzymatic antioxidant system in the body and they are the first defensive molecules in elimination of oxidant agents. As a result, thiol levels may be an earlier indicator for CAD. There is limited data on the relation of dietary factors with thiol/disulfide homeostasis in patients wi...

Background: Despite the efforts to reduce smoking, unfortunately there is a common belief in society to avoid smoking cessation or quitting smoking for weight control. As well as many negative effects of smoking, people continue to smoke instead of diet and life change. Nicotine plus high fat diet (HFD) induces intramyocellular lipid accumulation and mitochondrial abnormalities in obese mice. There is limited data in the relation of dietary fat content and metabolic syndrome i...

Introduction: Prolactinoma is the prolactin secreting tumor of the pituitary gland which exerts mainly hypogonadal complaints and sometimes symptoms due to mass effect. Meanwhile it was mentioned to cause metabolic abnormalities such as increased fasting plasma glucose (FPG), Low Density Lipoprotein(LDL) cholesterol and triglycerides(TG). We studied whether some of these metabolic parametres of prolactinoma patients could be changed after the therapy.Met...

Introduction: Bariatric surgery would end up with great alterations in homeostatic measures such as glucose and lipid metabolism and hormonal regulation, which of all are interweaved with some number of ways to each other. The hormonal modulation extands along a wide span starting from the change in gastrointestinal peptides, to the effect in insulin and other nutrient metabolism regulatory hormones and even the hormones establishing thyroid and calcium homeostasis. Secondary ...

: In this paper we present an 18-year-old patient with Klinefelter syndrome who has taurodontism. Klinefelter syndrome is the most common abnormality of sex chromosomes. It is characterized by hypogonadism, gynaecomastia, azoospermia or oligospermia, and increased levels of gonadotropins. Associated medical disorders can be categorized as follows; cancer, autoimmune disorders, intellectuel and psychiatric disorder, osteoporosis, endocrine disorders, venous disease and taurodon...

Fine-needle aspiration biopsy (FNAB) of the thyroid gland is the most effective examination in the evaluation of thyroid nodules. To describe our experience with FNAB of the thyroid and compare the results with palpation versus ultrasonography-guided (UG) methods in an endemic goiter area in Turkey.Methods: We studied on 176 patients whom 140 were females and 36 males, submitted to FNAB of thyroid nodules at outpatient clinic of a university hospital in ...